Alzheimer’s Disease | Nagitsuji Hospital

Alzheimer’s DiseasePlan No.: PB5190009

We provide treatment for Alzheimer’s disease using intravenous infusions of adipose-derived mesenchymal stem cells.

Medical image of a stethoscope and laptop

Purpose of Treatment

Through actions such as differentiation into nerve cells, repair of nerve cells, improvement of blood flow and suppression of inflammation, adipose-derived mesenchymal stem cells are expected to help repair the damaged brain.

What Is Alzheimer’s Disease?

In Alzheimer’s disease, amyloid beta and tau proteins accumulate in the brain, gradually placing a burden on nerve cells. Recent research worldwide has shown that chronic neuroinflammation and oxidative stress are involved in progression, drawing attention to approaches that improve the neural environment.

Illustration of an artery with a stent inserted

When the environment supporting nerve cells is disrupted, inflammation, reactive oxygen species and reduced blood flow are thought to combine to weaken cell function.

Rather than “curing” the disease,
it is important to “create an environment in which nerves can function more easily.”

Our Treatment

We provide intravenous infusions of adipose-derived mesenchymal stem cells with the aim of repairing and regenerating nerve cells and improving the brain environment. Research suggests the following potential advantages compared with exosomes and allogeneic stem cells:

High Level of Safety Because the Cells Are Autologous
Because the cells “act while alive,” they secrete a broad range of factors.
Potential for Long-Term Regulation of Inflammation and Cell Protection

Expected Effects

The following have been reported as expected effects, with increasing recognition particularly in relation to safety:

Suppression of Neuroinflammation
Reduction of Oxidative Stress
Amyloid Burden:
A Tendency toward Reduction
A Tendency toward Improved Memory Function

By “improving the neural environment,”
the aim is to promote repair of the damaged brain.